Protein Info for GFF4703 in Sphingobium sp. HT1-2

Annotation: Transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 transmembrane" amino acids 219 to 241 (23 residues), see Phobius details PF00126: HTH_1" amino acids 17 to 75 (59 residues), 66.8 bits, see alignment E=1.3e-22 PF03466: LysR_substrate" amino acids 98 to 269 (172 residues), 55.7 bits, see alignment E=4.6e-19

Best Hits

KEGG orthology group: None (inferred from 50% identity to bur:Bcep18194_B1830)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (293 amino acids)

>GFF4703 Transcriptional regulator, LysR family (Sphingobium sp. HT1-2)
MISAISNLDDKMNTLDLDAVKIFLMIVELRSFTKAAAAMDLAQSAVSTKLRKLETELGHQ
LVERTPRSVQLSAAGAMFLQPARDLITAHDLALSSFGSRQRRLSIGFSNHIFGPQIPAML
SRLHSQDPGLVLEMKVGTTREIMEAMDCGSIGAAFVLPLDETRRGGEVVGQQAFGWMAAP
GWTWDRSTSLPIAVQPSPCAVRAMTIRALEDASIPWMEAFVGGGVATIAAAAAAGLAVAA
LGRQVAPADVIDMGAALHLPPLPAQDILLYSSLSDGASRKSLRLIGAMFGSVL