Protein Info for GFF4702 in Variovorax sp. SCN45

Annotation: ABC transporter, ATP-binding protein (cluster 1, maltose/g3p/polyamine/iron); ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 379 PF00005: ABC_tran" amino acids 32 to 173 (142 residues), 115.4 bits, see alignment E=6.5e-37 PF17912: OB_MalK" amino acids 247 to 298 (52 residues), 30.3 bits, see alignment 1.2e-10 PF08402: TOBE_2" amino acids 291 to 363 (73 residues), 32.2 bits, see alignment E=1.9e-11

Best Hits

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 85% identity to vpe:Varpa_4067)

Predicted SEED Role

"Various polyols ABC transporter, ATP-binding component" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (379 amino acids)

>GFF4702 ABC transporter, ATP-binding protein (cluster 1, maltose/g3p/polyamine/iron); ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate) (Variovorax sp. SCN45)
MTAVPHFPEKQNMSAISCHNIIKRYGDTQVVHQFDLDVSDNEFVVFLGPSGCGKSTILRM
LAGLEDISGGDLMIGGQRVNDLPPQERGIAMVFQNYALYPHMSVRDNIAFGLKRQKVPRA
EIDARIKEVSDTLGLERYLQRKPAELSGGQQQRVAIARAMIKTPKVFLFDEPLSNLDAKL
RNHMRIEIARLHQALKTTTVYVTHDQHEAMTLADRIVLLRDGRIEQVGSPREIFERPRSA
FVAGFIGTPPMNLVEMRVRDAGGYFELAGREGTVRVDSRRFALEGRERVTLGVRPAHLQA
DTQDGRDGGFAGEVQLIEYLGNEVLVSFGQGESEIAALMPSALCPRLRDAVRFVADPAQV
HLFDIDTGASLLRADNPLH