Protein Info for PS417_00240 in Pseudomonas simiae WCS417

Annotation: anhydrase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 180 PF00132: Hexapep" amino acids 95 to 128 (34 residues), 27.5 bits, see alignment 8.9e-11

Best Hits

Swiss-Prot: 63% identical to YRDA_SHIFL: Protein YrdA (yrdA) from Shigella flexneri

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU0047)

Predicted SEED Role

"carbonic anhydrase, family 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U2Y5 at UniProt or InterPro

Protein Sequence (180 amino acids)

>PS417_00240 anhydrase (Pseudomonas simiae WCS417)
MTLRTYQNHTPTLGAGAFVDISAVVIGDVEIGADSSVWPLTVIRGDMHRIRIGARTSVQD
GCVLHITHAGPFNPDGFPLLIGDDVTIAHKVMLHGCTVGNRILIGMGSTVMDGAVVEDDV
IIGAGSLVPPGKKLESGFLYVGSPVKQIRPLTDKERAFFTYSAANYVKLKDLHLAEGFDR