Protein Info for PS417_23865 in Pseudomonas simiae WCS417

Annotation: XRE family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 TIGR00230: sugar fermentation stimulation protein" amino acids 4 to 231 (228 residues), 221.8 bits, see alignment E=4.1e-70 PF17746: SfsA_N" amino acids 13 to 80 (68 residues), 73 bits, see alignment E=1.7e-24 PF03749: SfsA" amino acids 84 to 223 (140 residues), 158 bits, see alignment E=1.3e-50

Best Hits

Swiss-Prot: 96% identical to SFSA_PSEFS: Sugar fermentation stimulation protein homolog (sfsA) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K06206, sugar fermentation stimulation protein A (inferred from 96% identity to pfs:PFLU5231)

Predicted SEED Role

"Sugar/maltose fermentation stimulation protein homolog" in subsystem Fermentations: Mixed acid

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See U1SRM2 at UniProt or InterPro

Protein Sequence (236 amino acids)

>PS417_23865 XRE family transcriptional regulator (Pseudomonas simiae WCS417)
MRFHPPLEEARLIRRYKRFLTDIETVTGELLTIHCPNTGSMLNCMVEGGQVWFSRSNDPK
RKLPGTWEIAETPQGRLACVNTARANQLVEEALRAGVITELNGFTALKREVPYGQEKSRI
DFRLDYPDGAAYVEVKSVTLGFDGTSIAAFPDAVTQRGAKHLRELAHLARDGVRAVQLYC
VNLSGIDAVRPAVEIDAAYAAALREAEAAGVEVLAYGVRVTCEEIYVDRRLDVLLD