Protein Info for GFF4659 in Xanthobacter sp. DMC5

Annotation: Protein-methionine-sulfoxide reductase catalytic subunit MsrP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 signal peptide" amino acids 1 to 50 (50 residues), see Phobius details PF00174: Oxidored_molyb" amino acids 106 to 262 (157 residues), 95.5 bits, see alignment E=1.4e-31

Best Hits

Swiss-Prot: 48% identical to MSRP_METCA: Protein-methionine-sulfoxide reductase catalytic subunit MsrP (msrP) from Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

KEGG orthology group: K07147, (no description) (inferred from 82% identity to xau:Xaut_2734)

Predicted SEED Role

"Putative sulfite oxidase subunit YedY"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (325 amino acids)

>GFF4659 Protein-methionine-sulfoxide reductase catalytic subunit MsrP (Xanthobacter sp. DMC5)
MLIRSRRGWELPESAATPEDVYLNRRQAMGAGAMLLAGLGAGTLSSPAAAQRVGDVPDPS
ASLYPAPRNPRYTLERPVTPEAKSSLVNNYYEFSYGKVVGPSMTRFQRRPWLVKIDGLVE
KPQEMGIDDLFKKVKFEERLYRHRCVEAWSMAVPWTGFPMKDLVALAAPTSGAKYIKMET
FLDPKVAPNQRDFRYTWPYVEGLTLEEATNELAFLVTGVYGKPAPNQFGAPLRLVLPWKY
GFKSIKGIVRFTFTDKQPVSFWEQLQGSEYGFWANVNPKVPHPRWSQASEEDIATGERVP
TVIFNGYGEYVADLYKGRETQKIWF