Protein Info for GFF4659 in Sphingobium sp. HT1-2

Annotation: Arsenical-resistance protein ACR3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 38 to 58 (21 residues), see Phobius details amino acids 79 to 102 (24 residues), see Phobius details amino acids 114 to 136 (23 residues), see Phobius details amino acids 149 to 172 (24 residues), see Phobius details amino acids 178 to 197 (20 residues), see Phobius details amino acids 211 to 233 (23 residues), see Phobius details amino acids 244 to 266 (23 residues), see Phobius details amino acids 273 to 301 (29 residues), see Phobius details amino acids 307 to 329 (23 residues), see Phobius details TIGR00832: arsenical-resistance protein" amino acids 1 to 328 (328 residues), 372.6 bits, see alignment E=9.8e-116 PF01758: SBF" amino acids 49 to 241 (193 residues), 117.9 bits, see alignment E=2.3e-38

Best Hits

KEGG orthology group: K03325, arsenite transporter, ACR3 family (inferred from 77% identity to sal:Sala_2538)

Predicted SEED Role

"Arsenical-resistance protein ACR3" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>GFF4659 Arsenical-resistance protein ACR3 (Sphingobium sp. HT1-2)
MSLFERYLSLWVALCIVVGIGLGHLLPGAFEAIAALEIANVNLVVAGLIWLMIIPMLLRV
DFGALHSLRQHWRGIGITLVVNWAIKPFSMALLGTFFLGHLFAPMLPEGVSSSYIAGLIL
LAAAPCTAMVFVWSNLVDGEPNYTLSQVALNDLIMVLAFAPLVGLLLGVASITVPWSTLA
LSVGLYIVVPVVISQLLRRVLLRGGEKQLQHFLSAIGPISLASLLLTLVLLFGFQGEQII
RQPLVIALIAVPILFQVYLNAGIAYWLSRRFGVAWCVAGPSALIGASNFFELAVAAAISL
FGLSSGAALATVVGVLVEVPVMLSIVALVKRTRPWYEKGISA