Protein Info for GFF4642 in Xanthobacter sp. DMC5

Annotation: Anaerobic glycerol-3-phosphate dehydrogenase subunit C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 PF13183: Fer4_8" amino acids 34 to 109 (76 residues), 31.8 bits, see alignment E=2.5e-11 PF13534: Fer4_17" amino acids 36 to 111 (76 residues), 30.6 bits, see alignment E=6.2e-11 PF02754: CCG" amino acids 214 to 296 (83 residues), 13 bits, see alignment E=1.4e-05

Best Hits

KEGG orthology group: K06911, (no description) (inferred from 88% identity to xau:Xaut_2720)

Predicted SEED Role

"Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD" in subsystem Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 1.1.99.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.14

Use Curated BLAST to search for 1.1.99.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (450 amino acids)

>GFF4642 Anaerobic glycerol-3-phosphate dehydrogenase subunit C (Xanthobacter sp. DMC5)
MKTFLDWSAYDTYGIGDAYSGIPATGGNYAKAVAVCMHSRDCQNTGKGVMCPSYRITGDR
AHSTEARVAAFKAALNDGSDAAAFADPRLDEAMDLCVSCKACKKECPSAVDMTLIKTEYL
AQRHEIKGVPLRTRLFGGVPEWTGRHRRLLRLAILLRNRVPTMARLAERFLGITARRPIP
EPAPAAYVAPPAAPHLAERGDVILFVDTFCHHFEPEVAEAAREVLTFAGYRVRIAKPDPA
DAEPDRPLCCGRTYLTTGMVEKARSEGRRVLAAFEGEIAAGTPIIGLEPSCLLSLRDELY
SLGLGPKIGALGKQLYLFEEFLAREHQNRGLRLKLKALPGAKAVLHGHCHQKAFGVMKAT
RKVLSFIPGFSYDIVETSCCGMAGSFGLEAEHYDASMQMAEIALLPAMRAAPDDAPLIAN
GFSCRHQIEHGSGRKARHIALLIRDALDRD