Protein Info for GFF4630 in Sphingobium sp. HT1-2

Annotation: FIG138928: iron-regulated membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 188 to 211 (24 residues), see Phobius details amino acids 340 to 361 (22 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details amino acids 414 to 431 (18 residues), see Phobius details amino acids 438 to 457 (20 residues), see Phobius details amino acids 463 to 482 (20 residues), see Phobius details PF03929: PepSY_TM" amino acids 17 to 363 (347 residues), 222.8 bits, see alignment E=4.5e-70

Best Hits

KEGG orthology group: None (inferred from 51% identity to gdj:Gdia_2589)

Predicted SEED Role

"FIG138928: iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (504 amino acids)

>GFF4630 FIG138928: iron-regulated membrane protein (Sphingobium sp. HT1-2)
MSGASAMVRDGVRQAMAWLHGWTGLLLGYVLFVMCLAGTLSVFKPEIGRWMRPEVTAQAD
GKSAIVAATGWLSKHAPGSTGWYLTAPDGRANTVEASYDQGSDYLYRALDPVTGAPVARE
TLGGEFFYRLHFELEIPYPWGRLLASLAAMVMLVALVTGIIAHKRIFKDFFTFRPAKGQR
SWLDGHNATGVLAMPFHLMITFTGLLTLASLNMPWPISAGYGDKVMEMYEALAPGSVTRP
AAGKPASLAPIAPMLTAAERAFGGGHVGRVYVFNPGDAASIVTVYQSDADSIGYMRGQAS
FDGATGRLLKSWVERRPAMRTYQVVYGLHMARFAPMATRWLYVLGGAMLTLAISTGMVLW
IAKRRERQPLSIGNRILERLNVGVITGVSLGAVAYFIANRLLPIGMAGRPDAEVSVALWT
AAAAVLAGLALRPAIGWPLMMGLLAFACVLAAVLGPVWSTEPILLTGNLLFLVMAVALAL
IVRRQMRRRNAPTPARRRMREQPA