Protein Info for PS417_23680 in Pseudomonas simiae WCS417

Annotation: AraC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 PF14525: AraC_binding_2" amino acids 14 to 195 (182 residues), 135.6 bits, see alignment E=2.3e-43 PF12833: HTH_18" amino acids 241 to 320 (80 residues), 68 bits, see alignment E=1.1e-22

Best Hits

KEGG orthology group: None (inferred from 96% identity to pfs:PFLU5193)

Predicted SEED Role

"benABC operon transcriptional activator BenR" in subsystem Benzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UKV5 at UniProt or InterPro

Protein Sequence (326 amino acids)

>PS417_23680 AraC family transcriptional regulator (Pseudomonas simiae WCS417)
MSSQTIQRFDLEGARSWMSGICGPHRLATATPERLRFHHSANVFKSRATTLGVIEYGTDV
TIDIEDAEHFSSYSLSLPLVGEQELSKNGERLSSNRDQGVIISPNEHQVLAISGDCRKLQ
VVITRAAMGESLEGLLQRPIDAPLRFESVMDAVDGASAAWWRMARYFIAELEHGSELYEQ
PAFTRDLESSLIKGLILAQPNNYSEELRDMLGVKLPHYLIRARQYIHDNAREAVHLEDLE
AAAGVSRFKLFDAFRKYFALSPMAYLKKHRLSAVRQEILEHGSTRTISEIALGWGFTHLG
RFSAEYRKLFDESPSQTQQRKRMRSI