Protein Info for GFF4625 in Variovorax sp. SCN45

Annotation: Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.33)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 74 to 95 (22 residues), see Phobius details amino acids 107 to 127 (21 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 168 to 186 (19 residues), see Phobius details amino acids 192 to 212 (21 residues), see Phobius details amino acids 223 to 241 (19 residues), see Phobius details amino acids 247 to 266 (20 residues), see Phobius details amino acids 312 to 330 (19 residues), see Phobius details amino acids 336 to 355 (20 residues), see Phobius details PF00953: Glycos_transf_4" amino acids 81 to 238 (158 residues), 116.3 bits, see alignment E=6.9e-38

Best Hits

KEGG orthology group: None (inferred from 94% identity to vpe:Varpa_0797)

Predicted SEED Role

"Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-)" in subsystem Methicillin resistance in Staphylococci or Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (365 amino acids)

>GFF4625 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.33) (Variovorax sp. SCN45)
MIALIVISFFVAAFSVQVFMRRARRHARIYGADMPQRFHKGHVPRLGGAGILLGMGVAWL
AAGVTGTDPFNVSWPVTTSMLTLLCIAPAVLGGIVEDVTQRVKVRYRLGLTIGSALLVCW
LLGLGVARTGFETVDGWLAMIPFATVLFAALAIGGLPHAFNIIDGYNGLAGTVAVLVCLA
ISHVALQVGDRQLAAMVVCLVGATFGFLVWNYPRGKIFAGDGGAYVWGMVIAVACVTLVQ
RHRVVSPWFPMLLLIYPVWETLFSIYRKLARGQSPGTADALHFHQLIFRRIVRVAFADDE
ARQLLARNNRTSPYLWMFAAMSVVPAVLFWNNTYVLIFFCLLFITTYVGAYLMIVRFKVP
RWLRP