Protein Info for GFF4621 in Xanthobacter sp. DMC5

Annotation: putative multidrug ABC transporter permease YbhS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 transmembrane" amino acids 30 to 50 (21 residues), see Phobius details amino acids 185 to 206 (22 residues), see Phobius details amino acids 236 to 257 (22 residues), see Phobius details amino acids 263 to 285 (23 residues), see Phobius details amino acids 298 to 321 (24 residues), see Phobius details amino acids 355 to 373 (19 residues), see Phobius details PF12679: ABC2_membrane_2" amino acids 17 to 375 (359 residues), 64 bits, see alignment E=2.9e-21 PF12698: ABC2_membrane_3" amino acids 30 to 370 (341 residues), 163.2 bits, see alignment E=1.9e-51 PF12730: ABC2_membrane_4" amino acids 163 to 301 (139 residues), 27.9 bits, see alignment E=4.4e-10 PF01061: ABC2_membrane" amino acids 182 to 342 (161 residues), 111.5 bits, see alignment E=8.9e-36

Best Hits

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 89% identity to xau:Xaut_0458)

Predicted SEED Role

"ABC-type multidrug transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>GFF4621 putative multidrug ABC transporter permease YbhS (Xanthobacter sp. DMC5)
MSVRAARGGFFTRVGAMIVKEFIQLRRDRVTFATMIMIPLLQLILFGYAINTTPRHLPTA
VFTHENNEVSRAILAALRNTAFFSFVREVKSAEDAEHMIRAGEVLFFVEIPAGFERALRR
GDAPQLLVAADATDPVGSANALAALAGVVNSALVRERFVDAPGSAAFEIVQHRRYNPAGT
SQLNIVPGLLGTILTMTMLIFTALSVTREIERGTMESLLSMPIHPVEIMLGKITPYVLVG
ILQALLIMGAGMILFGVPLEGSAILLAVATLLFIVVNLSIGYTFSTLAQNQLQAVQMSFM
FFLPSILLSGFMFPFSGMPLWAQWIGEGLPLTHYLRMVRGILLKGSGFSDLTTDAGALVV
LMLVAMAIAVARFRQTLD