Protein Info for PS417_23605 in Pseudomonas simiae WCS417

Annotation: permease DsdX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 49 to 69 (21 residues), see Phobius details amino acids 82 to 100 (19 residues), see Phobius details amino acids 122 to 149 (28 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details amino acids 199 to 219 (21 residues), see Phobius details amino acids 249 to 271 (23 residues), see Phobius details amino acids 283 to 307 (25 residues), see Phobius details amino acids 323 to 341 (19 residues), see Phobius details amino acids 355 to 375 (21 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details amino acids 408 to 430 (23 residues), see Phobius details amino acids 442 to 463 (22 residues), see Phobius details PF02447: GntP_permease" amino acids 28 to 461 (434 residues), 506 bits, see alignment E=8.7e-156 TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 30 to 465 (436 residues), 464 bits, see alignment E=2.8e-143 PF03600: CitMHS" amino acids 43 to 413 (371 residues), 41.6 bits, see alignment E=8.6e-15

Best Hits

KEGG orthology group: K03299, gluconate:H+ symporter, GntP family (inferred from 98% identity to pfs:PFLU5180)

Predicted SEED Role

"Gluconate transporter family protein" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UNE3 at UniProt or InterPro

Protein Sequence (467 amino acids)

>PS417_23605 permease DsdX (Pseudomonas simiae WCS417)
MIYEFHNQFDVTLSEEYRMAASPGFGLLAYAAIAIIALIVLIARYRLNPFIVITLVSIGL
ALMAGMPADTIMGSYEAGVGKTLGHIALVVALGTMLGKMMAESGGAEQVARTLINRFGER
NAHWAMVCIAFLVGLPLFFEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHALVP
PHPAAMMAVLAYNASVGQTVLYAILIGIPTAIIAGPVYAKFIVPRIHLPAENPLERQFID
REPRTRLPSFTLTMGTILLPVVLMMIGGWANVISSPGSAFNQFLLFIGNSVIALLVATLV
SFWTLGIAQGFNRESILKFTNECLAPTASITLLVGAGGGLNRILVDAGVTNEILGLAHAF
QLSPLVMGWLFAALMRIATGSATVAMTTASGVVAPVAMGLGYPHPELLVLATGAGSVIFS
HVNDGGFWLIKEYFNMTVIQTFKTWTVLETLISVVAFGLTYGLSCIL