Protein Info for GFF4609 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 682 transmembrane" amino acids 34 to 55 (22 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 219 to 242 (24 residues), see Phobius details amino acids 252 to 276 (25 residues), see Phobius details amino acids 576 to 597 (22 residues), see Phobius details amino acids 616 to 636 (21 residues), see Phobius details amino acids 655 to 679 (25 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 2 to 677 (676 residues), 1238 bits, see alignment E=0 TIGR01494: HAD ATPase, P-type, family IC" amino acids 71 to 334 (264 residues), 126.4 bits, see alignment E=1.1e-40 amino acids 372 to 604 (233 residues), 162.2 bits, see alignment E=1.5e-51 PF00122: E1-E2_ATPase" amino acids 114 to 282 (169 residues), 112.3 bits, see alignment E=3.1e-36 PF00702: Hydrolase" amino acids 301 to 530 (230 residues), 104 bits, see alignment E=2.2e-33

Best Hits

Swiss-Prot: 100% identical to KDPB_SALEP: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Salmonella enteritidis PT4 (strain P125109)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 92% identity to cko:CKO_02464)

MetaCyc: 92% identical to K+ transporting P-type ATPase subunit KdpB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (682 amino acids)

>GFF4609 Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MSRKQLALFEPVLLVQALTDAVKKLSPRAQWRNPVMFVVWAGSVLTTLLTLAMVTGQIAG
SALFTGIISLWLWFTVLFANFAEALAEGRSKAQANSLKGVKKTAFARRLRAPRHDAQADN
VPAAELRKGDIVLVKAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGT
RILSDWLVIACSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLW
PFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGD
VDVLLLDKTGTITLGNRQASDFIPARGVDERTLADAAQLASLADETPEGRSIVILAKQRF
NLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVESNGGHFPADVEQNV
ENVARLGATPLVVVEGAHVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAA
IAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQ
AAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYP
QLNALNVMGLHSPNSAILSAVIFNALIIIFLIPLALKGVSYKPLSASAMLRRNLWIYGLG
GLVVPFIGIKVIDVLLTLLGLA