Protein Info for GFF46 in Xanthobacter sp. DMC5

Annotation: Putrescine transport system permease protein PotH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 87 to 110 (24 residues), see Phobius details amino acids 122 to 143 (22 residues), see Phobius details amino acids 173 to 194 (22 residues), see Phobius details amino acids 222 to 244 (23 residues), see Phobius details amino acids 272 to 293 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 106 to 299 (194 residues), 58.4 bits, see alignment E=4.1e-20

Best Hits

KEGG orthology group: K11075, putrescine transport system permease protein (inferred from 94% identity to xau:Xaut_2942)

Predicted SEED Role

"Putrescine transport system permease protein PotH (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (305 amino acids)

>GFF46 Putrescine transport system permease protein PotH (Xanthobacter sp. DMC5)
MAMAGEKGRGRWVVIAVPYLWLLALFLAPFLIVFKISLSQDVVAQPPYAPQLDLSNGLAG
ITEFLSGLSFANYGYVLDFSNEFLEAYGSSLVIASISTLLLLLVGYPIAYGMARAPRSIQ
PTLLMLVILPFWTSFLIRVYAWIGILSPEGLLNQGLMALGVIDTPLEILNTNLAVYIGIV
YSYLPFMVLPLYSALEKLDLTLLEAAADLGCPPVKAFWKITFPLSIPGVAAGALLCFIPA
VGEFVIPDLLGGSDTLMIGKSLWTEFTVNRSWTVSSAVAVLLLLVLVIPIVIYQNIQQRE
LEAGK