Protein Info for GFF4590 in Xanthobacter sp. DMC5

Annotation: HTH-type transcriptional regulator HdfR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 transmembrane" amino acids 209 to 231 (23 residues), see Phobius details PF00126: HTH_1" amino acids 8 to 66 (59 residues), 72.7 bits, see alignment E=1.9e-24 PF03466: LysR_substrate" amino acids 89 to 278 (190 residues), 78.4 bits, see alignment E=5e-26

Best Hits

KEGG orthology group: None (inferred from 74% identity to xau:Xaut_0948)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>GFF4590 HTH-type transcriptional regulator HdfR (Xanthobacter sp. DMC5)
MMDPPLDLDSVRTFVHIAELESFTRAAEAMGTSQAAVSLKLKRLEGRLGCRLFDRTPRYV
QLSPRGASFLDQARALLELHDRTLASLSEQRRRLTIGISDHVAGPELPALIARMNSQDPQ
LVIEIRIGSSADLLQQFDRREIDSALIRLRSDRDDGSLIAEEQFGWFAAPGWQHRPDEPL
PIATMAEPCGVRALACRLLDDAGVKWREIFVGGGVMAVAAAVMAGLGVAALSPRMVPFGA
MDVGRRLGLPPLPRQPIMLHSRVKDGPSREALAALAAAFRGAART