Protein Info for GFF4583 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 789 transmembrane" amino acids 52 to 71 (20 residues), see Phobius details amino acids 77 to 100 (24 residues), see Phobius details amino acids 109 to 126 (18 residues), see Phobius details amino acids 132 to 148 (17 residues), see Phobius details amino acids 153 to 171 (19 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 348 to 508 (161 residues), 119.7 bits, see alignment E=5.1e-39 PF00990: GGDEF" amino acids 349 to 505 (157 residues), 134.8 bits, see alignment E=2.4e-43 PF00563: EAL" amino acids 530 to 761 (232 residues), 193.9 bits, see alignment E=2.8e-61

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (789 amino acids)

>GFF4583 hypothetical protein (Xanthobacter sp. DMC5)
MRGITGQVGNSDGLGGAEDVRLRAFGGEFVDKATEQRFRVACLEEARRHGRFLFAASVIL
NALFLMSDWRFAGTAHFVVAVSARFAVVALSLLCLVAVQIATTPGRMTAIYLVWLWGISA
AIAVLVSSHSDLALFVVMLLPTVFYLAVPIPFGWLVSGGFGASALLLYGYLDRSAGWQVG
VGLALAVAVLNTMLALIAARANRTERRFWSVVRAEREANEKLRASEDILENTFQAVPIPL
VVARLEDGRHIKSNEAARRFYGGTLDLPDAGGLCEASLGGEGAQSLRDRLRRDGIATEFE
TTVTLADGEERQVVMAAAVTPSGPSPNLVAALVDVTDRRAAERRARYAASHDALTGLPNR
SAFHEGLEAALARRKPGQGICVLLLDLDGLKDVNDTLGHDAGDAVLMETAHRLDALVDQP
ALIARLGGDEFVCAIEGPDPIGLGRRVAQSILAELRRPLLHAGRHFSTRASVGIAVCPEH
DCSYGELMKDADLALYAAKQQGRNRVVVYAPAMRQAVLERVALNRAMIGALADDEIVPYY
QPKVSLVTGQLAGVEALVRWRRSPHSILSPSAFEAALSDPELAVLIGERMVRRVASDVRG
WIELGYDCGRVAINLAPAQFTNRDLAPTLLRQFHAAGVEPSHFDVEITETVFLGRSSDHV
APILDELNRAGVRVALDDFGTGYAGLIHLKQLPIDTIKIDQSFVKDIERDAFDTAIVCAV
IELGRKLGMRVVAEGLETAGQARFLRDNGCELAQGFLFFRPLAAPEMTDLLRAERPDTAA
ARLALFGAN