Protein Info for PS417_23450 in Pseudomonas simiae WCS417

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 228 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 50 (19 residues), see Phobius details amino acids 62 to 80 (19 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 148 to 170 (23 residues), see Phobius details amino acids 204 to 227 (24 residues), see Phobius details PF04172: LrgB" amino acids 14 to 226 (213 residues), 237.8 bits, see alignment E=4.3e-75

Best Hits

Swiss-Prot: 36% identical to YWBG_BACSU: Uncharacterized protein YwbG (ywbG) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 89% identity to pfo:Pfl01_0900)

Predicted SEED Role

"CidA-associated membrane protein CidB" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U8Q6 at UniProt or InterPro

Protein Sequence (228 amino acids)

>PS417_23450 membrane protein (Pseudomonas simiae WCS417)
MKFELMPVFWLALTLSAYIFSRWIYRRTGRYLLSPLILVPVLLLAVAVPMNTAYAEYSAD
THWLMLVLGPVTVAFAVPIWQQRKLLARYWSALLLGMIAGSAASIATSFGLAKALALDPS
VALSLVPRSITTPFAMPVSSDLGGVPELTAVFVMFTGVFGAMLGGVLLKWLPLRTPLARG
ALFGVGAHGAGVSRAHEVGGEEGSVAGLVMVLTGLLNLFAAPLLAALL