Protein Info for GFF4580 in Xanthobacter sp. DMC5

Annotation: HTH-type transcriptional regulator CymR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 146 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR00738: Rrf2 family protein" amino acids 3 to 127 (125 residues), 78.1 bits, see alignment E=2.9e-26 PF02082: Rrf2" amino acids 4 to 128 (125 residues), 84.6 bits, see alignment E=3.5e-28

Best Hits

KEGG orthology group: None (inferred from 98% identity to xau:Xaut_0076)

Predicted SEED Role

"Predicted transcriptional regulator of cysteine synthase, Rrf2 family" in subsystem Rrf2 family transcriptional regulators

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (146 amino acids)

>GFF4580 HTH-type transcriptional regulator CymR (Xanthobacter sp. DMC5)
MPRLSDKSLLAIAAVVDVAVHARGAPVAAKALAARHGLPPRRLEPVLQALVHAGVLKGVR
GPRGGYELARERRRVSVAEIVRVVEGAEEEKEIILPPLVTEVVQPAVAAAEDTFDTALDG
VTLEDLCRAADDKGHGSEHERIDFAI