Protein Info for GFF4563 in Sphingobium sp. HT1-2

Annotation: ATP synthase delta chain (EC 3.6.3.14)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 184 PF00213: OSCP" amino acids 12 to 181 (170 residues), 178.9 bits, see alignment E=4.7e-57 TIGR01145: ATP synthase F1, delta subunit" amino acids 13 to 179 (167 residues), 133.8 bits, see alignment E=3.7e-43

Best Hits

Swiss-Prot: 65% identical to ATPD_SPHWW: ATP synthase subunit delta (atpH) from Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

KEGG orthology group: K02113, F-type H+-transporting ATPase subunit delta [EC: 3.6.3.14] (inferred from 92% identity to sch:Sphch_0070)

Predicted SEED Role

"ATP synthase delta chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (184 amino acids)

>GFF4563 ATP synthase delta chain (EC 3.6.3.14) (Sphingobium sp. HT1-2)
VETTGGIQASLSGRYAVALFDLARDGKTLDTVAASLAAIKAAIAESSDFKGLINSPVLSR
DAAGKTIAAVASAMSIDPLTTNFLGVLAQNRRLSQLPAVIRAYEALLSNHKGEARAEVTS
AHPLTKTQLTALAKGLKARVGRDVAVEAKVDPAILGGLVVKIGSQMIDSSIRTRLNSLAL
AMKG