Protein Info for GFF4561 in Xanthobacter sp. DMC5

Annotation: Virginiamycin B lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 880 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF17990: LodA_N" amino acids 43 to 247 (205 residues), 212.1 bits, see alignment E=1.5e-66 PF18417: LodA_C" amino acids 374 to 516 (143 residues), 106.1 bits, see alignment E=2.2e-34

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (880 amino acids)

>GFF4561 Virginiamycin B lyase (Xanthobacter sp. DMC5)
MGEGVLSRRAFVAGLSAGLAGATQASAAPGGIDPKRVARIAIHPAIGVARVGNSKDAFYF
GPEVPGGVPVGPFKDEAGAMARQAARFRLFAYDAQGRVLGEVTAREAEISWTLTVANTKA
LWYGIDIPFDLPGAPAAGRRNAKVADRASLAIVPGPRTVTGPGARPQRLDGGAFQGQSVN
LGEVMTDADGHLVVMPASGRCHPAPDAPPMSGYADNDGWADDTGDGPVDAVVRMGGRDFR
ADPAWLISVGPNYAPAIATSLVTLYDVVEATLVGAGVRKAPPTVFEDHVWPVFARLSDLQ
WVNAGFLAKFGFGSPRDFARPAFRARLADASPANAAFRAEILALFRDPASPEVRPDLEPQ
LYGDHLVLPPDVIEPRQWMTLTPLQYAHLRNWAAGRFTPGRPARMGRLEGIVLGGQPAAL
DRAALEACVGGPFHPGQEFPWIARVPWIWTADMRLVSTARAVDLTDYGTDMTSPEALSKS
GPLSRLGPGGITQWLGLPWQADWSSCRSGYQSSISPVLPAFWPARVPNTVLSEADYKVVM
DTARAIDERRAAFARRRDWERFISAPTRPPVLAAMAQDWFRLGVVADRPGPSDGSFPARM
KVETLVGFAREPDASYGANTLYPQVATFPLVVANSDDNSLRLVDAEGAVTVMALSAPLER
PEGMTRNLDGNLYVSCMNAGFVRRVTPKGEVSLFAEGFSQPMGIAGDRQGNLYVANWVEK
GFVSVITPDGKSRVLVPPEAGLVSPIGVVVAPDGALLVSWGGTSVARINATTGEILNPNW
LTGFRNPRQMAYDTSYRLYVADQLENAVRRFDPLGTPIPLILRGAELTMPFGLAFDLKGD
LYTSQTRGRLIKKVQLKGEVGIVSDFADGLPNPGGLVFIG