Protein Info for GFF455 in Variovorax sp. SCN45

Annotation: Uncharacterized UPF0721 integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 transmembrane" amino acids 16 to 43 (28 residues), see Phobius details amino acids 54 to 72 (19 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details amino acids 115 to 133 (19 residues), see Phobius details amino acids 152 to 174 (23 residues), see Phobius details amino acids 185 to 206 (22 residues), see Phobius details amino acids 219 to 241 (23 residues), see Phobius details amino acids 253 to 270 (18 residues), see Phobius details PF01925: TauE" amino acids 15 to 268 (254 residues), 183.9 bits, see alignment E=2.1e-58

Best Hits

KEGG orthology group: None (inferred from 91% identity to vap:Vapar_2544)

Predicted SEED Role

"Protein of unknown function DUF81" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (275 amino acids)

>GFF455 Uncharacterized UPF0721 integral membrane protein (Variovorax sp. SCN45)
VNIAALLDPLLIAELAALGLGTGFLAGLLGIGGGMMMVPFITIIMGHRGVPADLAVKIAI
ATSMATIIFTSVSSVRAHHKRGAVRWDIVKRLAPGIVIGSLAGSLGVFALLKGTALAIVF
ALFVGFSATQMFLDKKPKPTRQMPGTGGQLAAGGAIGFISGLVGAGGGFISVPFMTWCNV
AIHNAVATSAALGFPIAVANVAGYVISGQSVEGLPAGSFGYIWLPALAVIAACSVLTAPL
GARAAHSLPVKKLKRVFASILYVLAAYMLWKGLHG