Protein Info for GFF4524 in Variovorax sp. SCN45

Annotation: Uncharacterized symporter YhjB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 42 to 62 (21 residues), see Phobius details amino acids 73 to 98 (26 residues), see Phobius details amino acids 119 to 139 (21 residues), see Phobius details amino acids 154 to 176 (23 residues), see Phobius details amino acids 185 to 205 (21 residues), see Phobius details amino acids 233 to 252 (20 residues), see Phobius details amino acids 271 to 294 (24 residues), see Phobius details amino acids 317 to 345 (29 residues), see Phobius details amino acids 366 to 383 (18 residues), see Phobius details amino acids 389 to 409 (21 residues), see Phobius details amino acids 421 to 440 (20 residues), see Phobius details amino acids 459 to 478 (20 residues), see Phobius details

Best Hits

Swiss-Prot: 53% identical to YHJB_BACSU: Uncharacterized symporter YhjB (yhjB) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 64% identity to bpy:Bphyt_2389)

Predicted SEED Role

"Acetate permease ActP (cation/acetate symporter)" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (491 amino acids)

>GFF4524 Uncharacterized symporter YhjB (Variovorax sp. SCN45)
VNAALAVIALFVVGALGLAVLARRGRTMSLEQWALGGRGLGAIMVFLLMAGESFSTFTFL
GASGWSYSKGTPAFYILAYGGLAYLMAFWMLPAVWRYATTHKLVSFSDFFAHKYDSRPLG
VLVSIVALMGMVALLTIQLRGLGIIVSEASYGSIAPQVAIWIGTLVMVSYILFSGIHGSA
SIAIVKDVLILALAVFLGIYLPWHYYGGVTPMFTAIHAANPGFFEFPKEGLNLTWYNSTI
LLTALGYYLYPFNLTSVYAAKSASAVRRNTILMPLYQVVIAFLFLVGFAAILQVPGLKGS
EVDLALFGLVKHTFDPWFVGVIGGTGVLTALVPGSMILLTASTVIGKNVYKEGFAPHATD
KQVSRVARGVLPVFALVAVYFVLRGGTTIVAIAIFASSLLTQLLPSLLFSLMKKPFGNKH
AAFAGILAGGAVLGFMMTTGSNLGTLFPAAPVVFKSLNTGLVALATNALVFVLVALFTPR
IVPRGAAPQPA