Protein Info for GFF4521 in Xanthobacter sp. DMC5

Annotation: Chemotaxis protein methyltransferase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 PF03705: CheR_N" amino acids 5 to 56 (52 residues), 38 bits, see alignment 2.1e-13 PF01739: CheR" amino acids 72 to 258 (187 residues), 168 bits, see alignment E=3.4e-53

Best Hits

KEGG orthology group: K00575, chemotaxis protein methyltransferase CheR [EC: 2.1.1.80] (inferred from 65% identity to azc:AZC_0665)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (281 amino acids)

>GFF4521 Chemotaxis protein methyltransferase 1 (Xanthobacter sp. DMC5)
MIRPADYEFFARFLKEKSGLILTDDKHYLLESRLIPLLNRFAIPDFARLAEILKSNEAPI
IAEAVVEAMTTNESLFFRDKVPFEDMARSLLPALCAARLKTHTLRIWCAAASTGQEPYSI
AMMLAERPELTGGRRVQILGTDISSDVLERARAGRYNQFEVQRGLSVQQLLKYFVKSGDW
WEVIPQLKSVVEYRKFNLLEPFGGLGTFDLIMCRNVLIYFDVPTKADILLRMSRQLAPDG
FLQLGGAETAIGICDAFRPLPDHRGTYVHTRAPSTIVAARR