Protein Info for GFF4520 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: ATP-dependent Clp protease adaptor protein ClpS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 119 PF02617: ClpS" amino acids 36 to 113 (78 residues), 116.3 bits, see alignment E=2.1e-38

Best Hits

Swiss-Prot: 72% identical to CLPS_ACIAC: ATP-dependent Clp protease adapter protein ClpS (clpS) from Acidovorax citrulli (strain AAC00-1)

KEGG orthology group: K06891, ATP-dependent Clp protease adaptor protein ClpS (inferred from 75% identity to pna:Pnap_1933)

Predicted SEED Role

"ATP-dependent Clp protease adaptor protein ClpS" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (119 amino acids)

>GFF4520 ATP-dependent Clp protease adaptor protein ClpS (Hydrogenophaga sp. GW460-11-11-14-LB1)
MATQNPKKPPNPVVSPPSTGADDSVVLERRAQRTQPPQMFQVVLLNDDFTPMEFVVHVIQ
EFFSKDRETATQIMLKIHLEGKGICGVYSRDVASTKVDQVLQAARAAGHPLQCLSEPVE