Protein Info for GFF4513 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1143 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 190 to 213 (24 residues), see Phobius details PF05227: CHASE3" amino acids 48 to 182 (135 residues), 152.6 bits, see alignment E=1.9e-48 PF13185: GAF_2" amino acids 241 to 374 (134 residues), 56.2 bits, see alignment E=1.3e-18 PF01590: GAF" amino acids 243 to 374 (132 residues), 35.3 bits, see alignment E=4.6e-12 PF00512: HisKA" amino acids 474 to 541 (68 residues), 70.6 bits, see alignment 2.8e-23 PF02518: HATPase_c" amino acids 589 to 698 (110 residues), 101.4 bits, see alignment E=1.2e-32 PF00072: Response_reg" amino acids 753 to 860 (108 residues), 63.2 bits, see alignment E=7.3e-21 amino acids 874 to 984 (111 residues), 64.9 bits, see alignment E=2.2e-21 amino acids 1020 to 1137 (118 residues), 91.2 bits, see alignment E=1.5e-29

Best Hits

KEGG orthology group: None (inferred from 73% identity to swi:Swit_5353)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1143 amino acids)

>GFF4513 hypothetical protein (Sphingobium sp. HT1-2)
MISTARATASRTRLDSWSLVGLLLGLAFFITSGAIAYRNVATLRENDQAIRHTHGVLIAL
NDLLSSVQDAETGQRGYLLTGSEPYLEPYTDARRTMAGQLRMVAALTKDNPVQQESFGSL
KRHVDAKLSELEASIALRRDQGFDAALALVRSDRGKTEMDAIRNQLETMAREELRQRQLR
IEEMASASRAAVTSGLVTAALGAALTIAIFVLLRRNSRARARQEWLQSGLVGLSESMRGE
KSLEELGQAILAYLTRYLGFQGGALFKGDAGHFHRIATIGVPPDADIPLAFSAGEGLLGQ
VAADGQPIILSDVPDRYLTIGSAFGRDRPRHLVIVPARTDESVNAVLELGFFEPVGQSAL
DLLGEASTAIGIALRSARFRMRLEEALDETQRQASELQAQSEELRVSNEELEEQGRALKE
SQVRLEQQQVELEQTNSQLEEQAQTLENQRDELERAGASLAVKARELEQASQYKSDFLAN
MSHELRTPLNSLLILSKLLGDNPDGNLSDDQVKFARTIESSGNDLLTLINDILDLSKIEA
GHVQIQPETVSVQRLIGDIRHLFQPVADDRALALEIELAEGSPVAIETDRMRVEQILKNL
LSNAFKFTEKGSVRLEIAPAGEEGLSLAVTDTGIGISPDQQRSIFEAFQQADGTISRKFG
GTGLGLSISRELARLLGGAISLQSEPGQGSTFTLVIPRAYDPSRVAPRETARPMPAASVS
SAPAVPARPASIAPGWSVEDDRGAIADGRRLLLVIEDDTVFASIVRDLSRELDFQCIVAG
TAEEAVSLAQQFRPSAIVLDLGLPDQSGLTVLDRLKHDDETRHIPIHVISAADHSQTALS
LGAAGYLLKPVKREQLAEVLTGLQEKLAARMRRVLIVEDDPVQRDAVAQLLKSNAVEIVG
VGTAAECLQALREQTYDCMVLDLTLPDASGFELLETLSREGDHGFPPVIVYTGHDLSPDD
EQRLRRYSNSIIIKGAKSPERLLDEVSLFLHQVVSELPPEQRRMIQKARHRDAALEGRRI
LIVEDDVRNVYSLTSILEPRGAVVQIARNGREALDALAASLDDPARTIDLVLMDVMMPVM
DGLTATGEIRRDPRWAKLPVVMLTAKAMPDDQQRCLEAGANDYMAKPIDVDKLLSLVRVW
MPR