Protein Info for PS417_23055 in Pseudomonas simiae WCS417

Annotation: GntR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 234 PF00392: GntR" amino acids 3 to 66 (64 residues), 60.3 bits, see alignment E=1.7e-20 TIGR02404: trehalose operon repressor" amino acids 3 to 234 (232 residues), 320.9 bits, see alignment E=2.5e-100 PF07702: UTRA" amino acids 89 to 226 (138 residues), 106.7 bits, see alignment E=1.4e-34

Best Hits

KEGG orthology group: K03486, GntR family transcriptional regulator, trehalose operon transcriptional repressor (inferred from 99% identity to pfs:PFLU5041)

Predicted SEED Role

"Trehalose operon transcriptional repressor" in subsystem Trehalose Uptake and Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U160 at UniProt or InterPro

Protein Sequence (234 amino acids)

>PS417_23055 GntR family transcriptional regulator (Pseudomonas simiae WCS417)
MSKYNQIYTDLLASITTERLQRGTRLPSETELMDSYQASRGTVRRAIEQLQERGFAQKIH
GKGTFVLSPNPIEFQLGGIVSFHETHADLGDDVHTEVVEFTQFPLEGSLLQHIEAEPGTL
ITRIKRVRRIGGKRVILDINHFVADVIPGLDRSIAEQSIYAFIEQTLQLQIAYAQRTIEA
LPRGKDDQTHLDLEGQSHVIVVSNQTFLQDGRQFEYTESRHTLDKFYFSDIARR