Protein Info for GFF450 in Sphingobium sp. HT1-2

Annotation: SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 PF13489: Methyltransf_23" amino acids 41 to 168 (128 residues), 37.4 bits, see alignment E=7.8e-13 PF01209: Ubie_methyltran" amino acids 43 to 147 (105 residues), 40.8 bits, see alignment E=6e-14 PF01135: PCMT" amino acids 45 to 88 (44 residues), 21.4 bits, see alignment 6.8e-08 PF13847: Methyltransf_31" amino acids 46 to 148 (103 residues), 48.5 bits, see alignment E=2.6e-16 PF13649: Methyltransf_25" amino acids 50 to 144 (95 residues), 60.3 bits, see alignment E=8.9e-20 PF08242: Methyltransf_12" amino acids 51 to 146 (96 residues), 39.9 bits, see alignment E=2.1e-13 PF08241: Methyltransf_11" amino acids 51 to 148 (98 residues), 58 bits, see alignment E=4.4e-19

Best Hits

KEGG orthology group: None (inferred from 67% identity to rec:RHECIAT_PA0000348)

Predicted SEED Role

"Methyltransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (286 amino acids)

>GFF450 SAM-dependent methyltransferase (Sphingobium sp. HT1-2)
MAQPNVYQVSDWNGSSGERWVTHRQRLDAMLAPFGDAAIAAADARPGERVLDVGCGAGTS
SIALARQVGATGEVLGLDISGPLIALAQSQQPADLPVRYALADAGSATLTTHGFNLLFSR
FGVMFFDDPVASFAHMRRWLRPGGRIAFVCWRAAADNDWVRLPMGAIRDIVPPLAPPDPE
APGPFSFGDPARVTRILSDAGFAAIDLAPIDGVIPFGQGANREAALDDALAMAFEVGPLS
RALADQPADVRDRAAQAVRSAFAARPGETAILIDGAAWIVTATNPG