Protein Info for PS417_23025 in Pseudomonas simiae WCS417

Annotation: murein transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 486 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF00497: SBP_bac_3" amino acids 43 to 266 (224 residues), 71.8 bits, see alignment E=4.9e-24 PF01464: SLT" amino acids 293 to 400 (108 residues), 85.5 bits, see alignment E=2.1e-28

Best Hits

Swiss-Prot: 90% identical to MLTF_PSEF5: Membrane-bound lytic murein transglycosylase F (mltF) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)

KEGG orthology group: None (inferred from 99% identity to pfs:PFLU5035)

Predicted SEED Role

"Transglycosylase, Slt family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UEN1 at UniProt or InterPro

Protein Sequence (486 amino acids)

>PS417_23025 murein transglycosylase (Pseudomonas simiae WCS417)
MFSPTALRPRCAKWLIATGLFLMLSACVDKPSTLERIKEDGVLRVVTRNSPATYFQDRNG
ETGFEYELVKRFADDLGVKLEIETADNLDDLFGQLGKPNGPVLAAAGLVSSEQRQTQVRF
SHPYLEVTPQIIYRNGQSRPTNAADLVGKKIMVLKGSTHAEQLAELKKQNPAIEYEESDA
VEVVDLLRMVDEGQIDLTLVDSNEVAMNQVYFPNVRVAFDLGNASNQSWAVAAGEDNSLL
NEINSYLDKVEKNGTLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPKYEKHFRAYAKAE
KVDWRLLAAIGYQESLWQPAVTSKTGVRGLMMLTQNTAQAMGVSNRLDPKQSIMGGAKYL
AKIKDELDDSIAEPDRTWFALAAYNVGTGHLEDARTLAKREGLNPNKWLDVKKMLPRLSQ
KQWYSKTRYGYARGGEPVHFVANIRRYYDILTWVTQPQLEGNQVVEGNLHVPGVDKTKPP
EDNPQL