Protein Info for GFF4496 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 transmembrane" amino acids 15 to 34 (20 residues), see Phobius details amino acids 52 to 74 (23 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details amino acids 146 to 170 (25 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details amino acids 228 to 247 (20 residues), see Phobius details amino acids 259 to 280 (22 residues), see Phobius details amino acids 292 to 310 (19 residues), see Phobius details amino acids 316 to 338 (23 residues), see Phobius details amino acids 350 to 371 (22 residues), see Phobius details amino acids 377 to 396 (20 residues), see Phobius details PF05977: MFS_3" amino acids 8 to 524 (517 residues), 738.7 bits, see alignment E=3.4e-226 PF07690: MFS_1" amino acids 22 to 365 (344 residues), 122.3 bits, see alignment E=2.2e-39

Best Hits

KEGG orthology group: None (inferred from 92% identity to vpe:Varpa_0958)

Predicted SEED Role

"MFS permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (525 amino acids)

>GFF4496 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSEQSTRGAFAPLRQPVFAVLWAATVLGNVGSFMRDVASSWLVTDLSASPTAVALIQTAA
TLPVFLLAIPAGVLSDILDRRRFLIFVQLVLAAVSGTLLVLSHTGALTVEYLIALTFVGG
IGAALMGPTWQSIVPELVPRADLKGAVALNSLGINIARSIGPAAGGLILASFGAAATYGV
DVLSYVFVIAALLWWKRPAPADSGLSENFLGAFRAGLRYTRASKELHVVLLRAAVFFLFA
SSVWALLPLVARQMLGGSAGFYGVLLGAVGAGAIGGALVMPRLRARLDADGMLLLAALLT
AAVMGSLVFAPPKWLAVLLLLVLGLGWIIALTTLNGVAQSILPNWVRGRGLAVYLTVFNG
AMAAGSLGWGLVAQQIGVPATLVAGAVGLVVVGLVFHRVRLPAGEADLQASNHWPEPLLA
EPVAHDRGPVMIQIEYRIRKDDRPAFLQAMKRLSLERRRDGAYAWGLHEHTVDGERVIEW
FLVESWAEHLRQHHRVSQADADLQGEALRFHIGPGKPEVHHFLAI