Protein Info for GFF4490 in Sphingobium sp. HT1-2

Annotation: Copper resistance protein D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 transmembrane" amino acids 6 to 30 (25 residues), see Phobius details amino acids 47 to 70 (24 residues), see Phobius details amino acids 85 to 110 (26 residues), see Phobius details amino acids 119 to 139 (21 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 199 to 222 (24 residues), see Phobius details amino acids 234 to 254 (21 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details PF05425: CopD" amino acids 194 to 301 (108 residues), 85.3 bits, see alignment E=1.9e-28

Best Hits

KEGG orthology group: K07245, putative copper resistance protein D (inferred from 42% identity to rpf:Rpic12D_5103)

Predicted SEED Role

"Copper resistance protein D" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (311 amino acids)

>GFF4490 Copper resistance protein D (Sphingobium sp. HT1-2)
VPDIIAIAVRLGLFLDLMLLFGLPMFGLYTLRGTERASGSVLRFRSVLATIALAGIVLSI
LGMMVLAASMGGVPLDQVDRATVNLLISGTAIGTVWQVRVAALLLVLYFSIVGWRRPAFA
LWSLSATAAVALATLAWTGHGAADEGLRGWVHLGADITHLWAAGIWVGALFALCLLIFRP
AARMAIDHIHLSHRALDGFAKVGSVVVGLLILSGFINSWILIGPSRLGSLFASLYGLLLG
AKLILFGVMLTLAAANRFFLTPSLAAAIETGNTSSAIGTLRRSLAIETGCALVILALVAW
LGLLAPPASGM