Protein Info for GFF4472 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 674 transmembrane" amino acids 35 to 55 (21 residues), see Phobius details amino acids 61 to 80 (20 residues), see Phobius details amino acids 213 to 237 (25 residues), see Phobius details amino acids 246 to 269 (24 residues), see Phobius details amino acids 579 to 600 (22 residues), see Phobius details amino acids 608 to 627 (20 residues), see Phobius details amino acids 647 to 672 (26 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 16 to 668 (653 residues), 976.7 bits, see alignment E=5e-298 TIGR01494: HAD ATPase, P-type, family IC" amino acids 70 to 597 (528 residues), 244.6 bits, see alignment E=1.5e-76 PF00122: E1-E2_ATPase" amino acids 103 to 278 (176 residues), 111.5 bits, see alignment E=3.4e-36 PF00702: Hydrolase" amino acids 295 to 522 (228 residues), 93.7 bits, see alignment E=2e-30

Best Hits

Swiss-Prot: 78% identical to KDPB_XANCP: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 89% identity to adn:Alide_3011)

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (674 amino acids)

>GFF4472 Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNTTHANSSAGTGQSLKPALIDSFKKLAPQHAIQNPVMAVVWLGTVVTAVATIAGWTTAG
FGWAVTFILFATVLFANFAEAVAEARGRGQAASLRRARKDLVARRLSSSGREHAVPAAEL
RPGDLVVVEEGQLIPADGEIVEGLATINESAVTGESAPVLREAGTDRSGVIGGTKVLSDR
IVLRVTAEPGHSFLDRMIALVEGSNRQKTXXEIALGIVLAVMTLTFMIVVVTLPFIGGFV
DVQINVVLLVALLVCLIPTTIGGLLPAIGIAGMNRALKANVLAKSGKAVEVAGDVDVLLL
DKTGTITHGDRQATAFHAMAGVDAALLRQAAMLASLADPTPEGKSIVKLAREKGETLADP
EKAHFLPFTAQTRMSGVDLPDDRVIRKGALDAIAAHVKSLDGRVPAELEARVSEVARKGA
TPLVVSDGRHVLGVVELSDVIKHGIKERFARLREMGVKTVMITGDNKLTAAYIAADAGVD
DYIAEARPEDKLARIRAEQAGGRLVAMVGDGTNDAPALAQADVGLAMNSGTQAAKEAGNM
VDLDSDPAKLLAVVEIGKQQLITRGALTTFSLANDVSKYFAILPALFAAAIPSMAVLNVM
NLSSPNSAVLSALIFNALVIPALIPLALRGVRFKPASATHLLRNNMLIYGVGGVLLPFVA
IKLIDVVLSALFNL