Protein Info for GFF4468 in Xanthobacter sp. DMC5

Annotation: Vitamin B12 import ATP-binding protein BtuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 363 TIGR04406: LPS export ABC transporter ATP-binding protein" amino acids 127 to 363 (237 residues), 374.1 bits, see alignment E=1.2e-116 PF00005: ABC_tran" amino acids 142 to 288 (147 residues), 123.5 bits, see alignment E=9.7e-40

Best Hits

Predicted SEED Role

"Lipopolysaccharide ABC transporter, ATP-binding protein LptB" in subsystem KDO2-Lipid A biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (363 amino acids)

>GFF4468 Vitamin B12 import ATP-binding protein BtuD (Xanthobacter sp. DMC5)
LNVLSMFGKSKSGDSKSGGKSGSGSTRGGQDARQYDPREDDPRETDGGPLTAGDRDYREW
EEDDPRSDAGYDAGYETPARAAPDPRHRAYMPPDAAYGDDADAGYDYPSSYPGDGRDALP
FNSTGALAAFGLAKSYGGRKVVKDVSMNVRRGEAVGLLGPNGAGKTTCFYMVTGLVKADA
GRIELDGHDITPLPMYRRARLGVGYLPQEASIFRGLSVEDNIMGVLQVSEPNRARRREET
EALLEEFKITHVRKSPSIALSGGERRRLEIARALATKPAFMLLDEPFAGIDPIAVGDIQA
LVRHLTSRGIGVLITDHNVRETLGLIDRAYIIHSGAVLMEGDPEAIVSSPDVRRLYLGEE
FRL