Protein Info for GFF4465 in Sphingobium sp. HT1-2

Annotation: protein of unknown function DUF1622

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 147 transmembrane" amino acids 12 to 39 (28 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 88 to 110 (23 residues), see Phobius details PF07784: DUF1622" amino acids 34 to 109 (76 residues), 76.1 bits, see alignment E=8.7e-26

Best Hits

KEGG orthology group: None (inferred from 98% identity to sjp:SJA_C1-05130)

Predicted SEED Role

"protein of unknown function DUF1622"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (147 amino acids)

>GFF4465 protein of unknown function DUF1622 (Sphingobium sp. HT1-2)
MITIEADWLSAFFRLAVIGLELAGTLTILVGAGLATFLFARRARAGDRTEAYSAFRSALG
RSILLGLEFLVAGDIVKSLVINPTLDDLIVLAGLVLVRTFLSISLGVEINGHWPWEETRM
AREKARAASDGSPATAEAAGCGTALKR