Protein Info for GFF4451 in Variovorax sp. SCN45

Annotation: Permease of the drug/metabolite transporter (DMT) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 613 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 176 to 201 (26 residues), see Phobius details amino acids 217 to 238 (22 residues), see Phobius details amino acids 244 to 270 (27 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details amino acids 306 to 329 (24 residues), see Phobius details amino acids 339 to 358 (20 residues), see Phobius details amino acids 370 to 388 (19 residues), see Phobius details

Best Hits

KEGG orthology group: None (inferred from 78% identity to vpe:Varpa_0997)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (613 amino acids)

>GFF4451 Permease of the drug/metabolite transporter (DMT) superfamily (Variovorax sp. SCN45)
MVSKLVSLLSLLLALLLSGIATTAAASVPEQSIELTQGSVTTSVDGVRRTEPVDLSYHWD
RQHEGRPGFATFDLPFTLEATPETPWGIFIPRVGNVFEVQLNDALLQVYGNLERGNEADY
AKAPIYIPVPGRLLKQGENHLQIRLRADSGRRAGLSHVTIGPAAQVRSEMFESAYAWRFT
GSVLLAAFSLIVGGIALALWLTQVETTANGRPRREGLYFWAALAEFCWAVRVADGVIAEP
PLSWGVWGVLMAICYAGWVVSVMMFGCHIAGWGNDRRFRWVRWPMAAIVAGTAVFTTVAL
QREEPLWLTGWLAVEIVLVVALVGAFAIATVRKPNTEQLLVAGAALVTVAFAARDWLVIR
LSDAYGETTWVRYSSVFFGVALLLIVLRRFHAATVQARGSVAALAEQVAQRERELAATYA
ELEAAARDQARTHERERILRDMHDGVGSHISSAIRQLQSGQTSPGDLLRTLRDSLDQLKL
SIDSIHLPPGDVGALLAALRYRLEPRLAAAGIEFEWAVDEVDTVARLDAQTMRQLQFLLF
EAISNVLQHAHATVLRLEADMRGKTVQVRVIDNGQGYDATQVPRALAERAGAIGARLAVE
SRPGRTVVQLAFD