Protein Info for PS417_22750 in Pseudomonas simiae WCS417

Annotation: RND transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 376 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF00529: CusB_dom_1" amino acids 42 to 351 (310 residues), 33.1 bits, see alignment E=8.9e-12 TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 44 to 366 (323 residues), 262.1 bits, see alignment E=3e-82 PF13533: Biotin_lipoyl_2" amino acids 70 to 114 (45 residues), 27.1 bits, see alignment 5.8e-10 PF16576: HlyD_D23" amino acids 71 to 268 (198 residues), 119.9 bits, see alignment E=2e-38 PF13437: HlyD_3" amino acids 166 to 266 (101 residues), 73 bits, see alignment E=6e-24

Best Hits

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU4978)

Predicted SEED Role

"Probable RND efflux membrane fusion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U8D7 at UniProt or InterPro

Protein Sequence (376 amino acids)

>PS417_22750 RND transporter (Pseudomonas simiae WCS417)
MLRRRMLIMLGVVLLIVLLLAGYKAFSIYQQIQVFSKPKPAVSVAVATATEQPWQLRVSS
VGTLKALQGVNLSLEIAGTVKDVQFESGQKVKTGQPLVQLDSAVESALLETAQADLGLAQ
LDYGRGSQLVGSQAISKGEFDRLSAQLQKNKATVNQLKASLAKKHIVAPFGGTIGIRQVD
VGDYLASGTVIATLQDLSSLYVDFYIPEHAVPKVAPGQPVQVEVSAYPGEQFPGSISAIN
PKVENSTRNVLVRATLANPEGKLLPGMFTRLDVLLPNPAPQIVVPEGAITYTLYGNSVYA
VAEKKTEGGEVEKDADGKPLLIAERRFVETGERRGGLVLVSKGLKAGEQVVSAGQLKLDN
GTPIAISPDKNLPAGH