Protein Info for PS417_22730 in Pseudomonas simiae WCS417

Annotation: nitroreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 transmembrane" amino acids 110 to 129 (20 residues), see Phobius details PF00881: Nitroreductase" amino acids 10 to 163 (154 residues), 75.4 bits, see alignment E=3.1e-25

Best Hits

Swiss-Prot: 46% identical to YDJA_ECOLI: Putative NAD(P)H nitroreductase YdjA (ydjA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 97% identity to pfs:PFLU4972)

Predicted SEED Role

"Nitroreductase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UK98 at UniProt or InterPro

Protein Sequence (187 amino acids)

>PS417_22730 nitroreductase (Pseudomonas simiae WCS417)
MQALDALLNRVSVPRLLEPAPTQEQRDVLFAAAMRAPDHGQLRPWRFLTVEGAAREQMGT
LLAEAARLQDADAPQAAIDKAQNGPLRAPLVVVVIARLQEHFKVPKSEQLLAAACAAHGI
LLAAYAQGIGAVWRTGELSYSAHVAKGLGLTADEEVIGFLYLGTPQNPPRTAAKEDLTQF
VSAWTGL