Protein Info for GFF4432 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Allantoate amidohydrolase (EC 3.5.3.9)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03176: allantoate amidohydrolase
  • amino acids 1 to 411 (411 residues), 805.9 bits, E=5.8e-247
• TIGR01879: amidase, hydantoinase/carbamoylase family
  • amino acids 8 to 407 (400 residues), 613.6 bits, E=1.5e-188
• PF01546: Peptidase_M20
  • amino acids 79 to 405 (327 residues), 93.8 bits, E=1.4e-30
• PF07687: M20_dimer
  • amino acids 212 to 310 (99 residues), 22.5 bits, E=8.9e-09

Best Hits

Swiss-Prot: 89% identical to ALLC_ECOLI: Allantoate amidohydrolase (allC) from Escherichia coli (strain K12)

KEGG orthology group: K02083, allantoate deiminase [EC: 3.5.3.9] (inferred from 99% identity to sty:STY0575)

MetaCyc: 89% identical to allantoate amidohydrolase (Escherichia coli K-12 substr. MG1655)
Allantoate deiminase. [EC: 3.5.3.9]

Predicted SEED Role

"Allantoate amidohydrolase (EC 3.5.3.9)" in subsystem Allantoin Utilization (EC 3.5.3.9)

MetaCyc Pathways

• allantoin degradation IV (anaerobic) (8/9 steps found)
• allantoin degradation to glyoxylate II (5/5 steps found)
• allantoin degradation to glyoxylate III (5/5 steps found)
• allantoin degradation to ureidoglycolate II (ammonia producing) (4/4 steps found)
• superpathway of allantoin degradation in plants (6/8 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.9

Protein Sequence (411 amino acids)

>GFF4432 Allantoate amidohydrolase (EC 3.5.3.9) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MIKHFRHAIEETLPWLSSIGADPTGGMTRLLYSPEWLETQQQFKKRMAESGLETRFDDVG
NLYGRLCGTQFPEQVILSGSHIDTVVNGGNLDGQFGALAAWLALDWLKATYGAPLRTVEV
VSMAEEEGSRFPYVFWGSKNIFGLANPEEVRHIQDAKGTGFVDAMQACGFTLPAAPLAAR
TDIRAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVH
AFSRICSQSIEKAKQHGDPLVLTFGKVEPQPNTVNVVPGKTTFTIDCRHTDAAVLREFTE
QLENDMRAICDEMDISIDIDLWMDEAPVPMNAELVAALTRLCETEQLNYRIMHSGAGHDA
QIFAPRVPTCMIFVPSINGISHNPAERTNINDLAEGVKTLALMLHQLAWQK