Protein Info for GFF4429 in Sphingobium sp. HT1-2

Annotation: Integral membrane protein TerC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 13 to 34 (22 residues), see Phobius details amino acids 46 to 66 (21 residues), see Phobius details amino acids 86 to 104 (19 residues), see Phobius details amino acids 111 to 133 (23 residues), see Phobius details amino acids 139 to 158 (20 residues), see Phobius details amino acids 208 to 232 (25 residues), see Phobius details amino acids 238 to 258 (21 residues), see Phobius details amino acids 270 to 291 (22 residues), see Phobius details amino acids 297 to 316 (20 residues), see Phobius details TIGR03718: integral membrane protein, TerC family" amino acids 12 to 319 (308 residues), 412.3 bits, see alignment E=6.8e-128 PF03741: TerC" amino acids 78 to 285 (208 residues), 174.3 bits, see alignment E=1.1e-55

Best Hits

Swiss-Prot: 46% identical to Y082_RICBR: Uncharacterized membrane protein RBE_0082 (RBE_0082) from Rickettsia bellii (strain RML369-C)

KEGG orthology group: K05794, tellurite resistance protein TerC (inferred from 72% identity to ara:Arad_7982)

Predicted SEED Role

"Integral membrane protein TerC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>GFF4429 Integral membrane protein TerC (Sphingobium sp. HT1-2)
MDFLFVDWLGKPLWLWLSFLGIVIVMLAVDLGIVHRKSKEIGVTESLVTSAAYILLGLAF
GGWVWWYMGATAGMNYLTGFVVEKSLAMDNVFVIAMIFTYFAVPRLYQHRVLFWGILGVI
VLRAIMIGVGATLVEQFSWVLYVFAAFLIFTGVKMWLFADKEYDVAANPVLKFVRRHFRV
TDRLHGEHFWVKQADPATGKQAWFMTPLMLALLMVEIVDVVFAVDSVPAIFAITTDPFIV
YTSNIFAILGLRALYFALAAMVDRFHYLKYALAILLVFIGSKIFVADALGLAKIPPVASL
SVTFAILAAGIGWSLWKTRDQAAHPA