Protein Info for GFF4427 in Sphingobium sp. HT1-2

Annotation: FIG005935: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 transmembrane" amino acids 37 to 57 (21 residues), see Phobius details amino acids 65 to 83 (19 residues), see Phobius details amino acids 95 to 115 (21 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 151 to 169 (19 residues), see Phobius details amino acids 175 to 192 (18 residues), see Phobius details amino acids 213 to 236 (24 residues), see Phobius details PF01027: Bax1-I" amino acids 27 to 236 (210 residues), 185.8 bits, see alignment E=4.4e-59

Best Hits

Swiss-Prot: 46% identical to Y147_RICPR: Uncharacterized protein RP147 (RP147) from Rickettsia prowazekii (strain Madrid E)

KEGG orthology group: K06890, (no description) (inferred from 66% identity to swi:Swit_5385)

Predicted SEED Role

"FIG005935: membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (242 amino acids)

>GFF4427 FIG005935: membrane protein (Sphingobium sp. HT1-2)
MERYRSYPSANAHAASAATATFDAGLRRHMLGIYRNMGLGLAITGAVALGVASSPAIYEP
IFNTPLKWAAMFAPLAFVLFFSFRIERMSTAGARTAFFAFAAVMGISMASIFLVFTGQSI
ATTFFIAASMFLAMSLWGYTTGRDLSKWSTFLLMGLVGVVIASLVNLFLASSVLQLVLSI
VGVIVFTALTAFDTQRAKSDYLAYGGTQAAEKLAVMSALSLYLNLVNLFQLLLTFFGQRQ
EN