Protein Info for GFF4424 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details signal peptide" amino acids 35 to 35 (1 residues), see Phobius details PF13365: Trypsin_2" amino acids 97 to 236 (140 residues), 126.4 bits, see alignment E=3.9e-40 PF00089: Trypsin" amino acids 105 to 262 (158 residues), 59.8 bits, see alignment E=9.2e-20 PF13180: PDZ_2" amino acids 275 to 374 (100 residues), 46.2 bits, see alignment E=1.2e-15 PF00595: PDZ" amino acids 277 to 361 (85 residues), 26.5 bits, see alignment E=1.7e-09

Best Hits

KEGG orthology group: None (inferred from 73% identity to bmj:BMULJ_00932)

Predicted SEED Role

"Peptidase S1, chymotrypsin:PDZ/DHR/GLGF domain precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>GFF4424 hypothetical protein (Sphingobium sp. HT1-2)
MSSGMSPETAKLGFIGRCLLVTACAAALILLWRVLQPMAPADPASRLVTARGDLAGDEKA
TIALFEKARGSVVYISTSQLVEDAWSRNVFSVPRGTGSGLIWDGAGHVVTNFHVIQGASE
ATVQLADGRKFRASLVGASPSHDLALLKIGVALRRPAPVPIGTSEDLKVGQKVFAIGNPF
GLDWTLTTGIISALDRSLPSERGGPSIEHLIQTDAAINPGNSGGPLLDSSGRLIGINTAI
FSPSGASAGIGFAVPVATVMRVVPQLIKSGRYVRPALGVEADEQVNERLQAITGREGVYV
LSVRPGSPAARAGLVGITATPGGIVPGDRITAIDGEDVDSLGALLAKLDDRKVGNVVKLT
VSRGEAAREVPVELEAGT