Protein Info for GFF4422 in Sphingobium sp. HT1-2

Annotation: Sulfate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 601 transmembrane" amino acids 37 to 58 (22 residues), see Phobius details amino acids 64 to 79 (16 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 140 to 161 (22 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 280 to 304 (25 residues), see Phobius details amino acids 317 to 336 (20 residues), see Phobius details amino acids 356 to 394 (39 residues), see Phobius details amino acids 412 to 442 (31 residues), see Phobius details TIGR00815: sulfate permease" amino acids 20 to 561 (542 residues), 432.6 bits, see alignment E=1.1e-133 PF00916: Sulfate_transp" amino acids 33 to 416 (384 residues), 328.6 bits, see alignment E=4.7e-102 PF01740: STAS" amino acids 472 to 574 (103 residues), 49.7 bits, see alignment E=2.7e-17

Best Hits

KEGG orthology group: None (inferred from 65% identity to pgv:SL003B_4259)

Predicted SEED Role

"Sulfate permease" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (601 amino acids)

>GFF4422 Sulfate permease (Sphingobium sp. HT1-2)
MDGQAAADRRVMAKLAHYLPALAWARGYDRATLASDMTAAAIVTIMLIPQSLAYAMLAGL
PPEIGLYASVAPLLAYAAFGTSRTLAVGPVAVISLMTLTAASAIGAPGSPRFIAAALILA
LLSGLILLAMGLLRLGFLASLLSHPVVSGFITASGILIAASQMKSLLGVDGGGATLPELI
AGLASDLASIHPPTLAIGVSACAFLFWVRSGAKPLLIRLGIAPRVADLLAKTGPIAAVAA
STLAVLALELEDKGVRVVGQIPQSLPPLTLPLFDAQLWRQLAIPALLLSVIGFVESVSVS
QTLAAKRRQKIDPDQELIGLGAANVAAAFTGGYPVTGGFARSVVNFDAGAQTPAAGVYTA
AGILVAALFLTPLLAALPIATLAATIIVAVLSLVDLRKPVEIWRYSKPDFAAMLATILLT
LAVGVEAGIIAGVGLSLALYLWRASRPHAAIVGRVPETEHFRNVARHRVFTDPRVLTIRI
DESLTYLNARWLEEFILEQIAEKRDVRHLILMCSAVNAIDASALESLEMINRRLADAGVC
LHLSEVKGPVMDALERSHLLDGLSGKVWLSQHEAFTKVIALADREQESLAAPDLWAARGA
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