Protein Info for GFF4416 in Xanthobacter sp. DMC5

Annotation: Thiosulfate sulfurtransferase GlpE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 PF00581: Rhodanese" amino acids 13 to 101 (89 residues), 68.3 bits, see alignment E=2.1e-22 PF13857: Ank_5" amino acids 130 to 177 (48 residues), 27 bits, see alignment 1.4e-09 amino acids 189 to 243 (55 residues), 31.9 bits, see alignment E=4e-11 PF12796: Ank_2" amino acids 131 to 198 (68 residues), 46 bits, see alignment E=2e-15 amino acids 196 to 252 (57 residues), 28 bits, see alignment E=7.9e-10 PF00023: Ank" amino acids 136 to 167 (32 residues), 22.1 bits, see alignment 4.3e-08 amino acids 169 to 200 (32 residues), 22.1 bits, see alignment 4.2e-08 amino acids 202 to 229 (28 residues), 24.7 bits, see alignment (E = 6.6e-09) PF13606: Ank_3" amino acids 169 to 197 (29 residues), 18.8 bits, see alignment (E = 5e-07) amino acids 202 to 229 (28 residues), 17.5 bits, see alignment (E = 1.4e-06) PF13637: Ank_4" amino acids 174 to 223 (50 residues), 28.3 bits, see alignment 5e-10

Best Hits

KEGG orthology group: None (inferred from 73% identity to xau:Xaut_0147)

Predicted SEED Role

"Rhodanese domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (265 amino acids)

>GFF4416 Thiosulfate sulfurtransferase GlpE (Xanthobacter sp. DMC5)
MRQRTPFRRIGVEEAVAIVGTGKALLLDVRDANSYAAGHVEGARNMAFGNLGDIIGTTPK
AQPVVIYCYHGNASQEYAQALSDFGFSDVTSVDGGYEAWFNHAQAQTPAAALDPALSAWI
ASRGFPPDGLNATAENGMTPLMKACAEGLPDTVAALIAAGAALDIRNADGNTALWIACVG
DHLDIIEALVDAGIAIDSANDNGATALMYAASAGKAGVVERLLARGADPRPETLDGFSAL
DLASTIECLTLLRRATKEARVATPA