Protein Info for GFF4398 in Sphingobium sp. HT1-2
Annotation: RND efflux system, inner membrane transporter
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 50% identity to cvi:CV_3924)Predicted SEED Role
No annotation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1031 amino acids)
>GFF4398 RND efflux system, inner membrane transporter (Sphingobium sp. HT1-2) MSIDMKGINLSRWALTHQQMVGFLLVLAAVAGLFSYMALGRKEDPEFTVKTMMITVGWPG ATAQQMSQQVIKPIETVLTENIAEIDYVKSKARPGQATLNVTLISTVKSSAVPDIWYRIR KTVTDNRADLPNGVVGPAFNDEFGTTYGNIYAVTGDGFSYPVLKRYAETLRDRIQALPDV AKTQIIGAQDEAIYVTYDSARLAMSGISAQAIADALDTTNAVAASGIVEAGAERVRMQVT GDFASVEAIAATPIVANGKSVRLDAIAKVERKPVHPATFRMRFGAKDAVGVGISLRSDGD VARLGEDLKHTIAALQSEMPVGVDIHTVSDQTRVVDESVGEFTTSLIEAIVIVLAVNFLS LGWRPGIVVALCIPLVLAMTFVCMLYVGIDLQRISLGALIIALGLLVDDAIIVVEAVATH LEAGWTRTRAAVSAYSVTAVPMLVGTLITVAGFLPIAMSKATASEYVISLFQVIAISLIL SWVVAVIFTPFIAYHLLPQRADARDDAGEPEEQYEGRFYGWFRRMLDRCLDRRKTVVAVA LAMFVGSMLLFQIGVPRQFFPASDRPELVVDLQLSQNASFAQTQAVAARMEQLLARDDRV VSTTAYLGGGSPRFYLPLNVQTPDITLAELVLQTRDEEAREGVIASIQSLFATHFPEARG RVSRLENGPSVGQPVQYRVAGPDLTQIMPVAKRLEELIRADSHARDVNSDLGEPLKAIRV DLDQDKVRALGLSTQAVQQSLQAAIGGAGTTSFRDRDLALEVVLRLSAAERTDLGRIANL PISTPNGAVPLAQLGHVSAGSEPAVIYQRNRQPTITISADVEGEQASDLTKRIEPQIEAL RRDLPSGASIVKGGSEEQSSINQKATMAAVPFAIFVIVILLMLQLQNVKRMLVVLATGPL ALIGVALIMALFRIPFGFVAMLGSLALFGMVLRNSVILIAQIDTLSGHGLAMREAVREAA VHRLRPILLTALAAILAMIPLTRSTFWGPMAWAIMGGLMVATILTLIVLPALYELVFDRP QHRADSQEISA