Protein Info for GFF4395 in Variovorax sp. SCN45
Annotation: Octaprenyl diphosphate synthase (EC 2.5.1.90)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: None (inferred from 72% identity to pna:Pnap_4179)Predicted SEED Role
"Octaprenyl diphosphate synthase (EC 2.5.1.90)" (EC 2.5.1.90)
MetaCyc Pathways
- polyisoprenoid biosynthesis (E. coli) (5/5 steps found)
- octaprenyl diphosphate biosynthesis (1/1 steps found)
- superpathway of chorismate metabolism (42/59 steps found)
- superpathway of ubiquinol-8 biosynthesis (early decarboxylation) (7/12 steps found)
- superpathway of menaquinol-8 biosynthesis I (5/10 steps found)
- superpathway of demethylmenaquinol-8 biosynthesis I (4/9 steps found)
- superpathway of menaquinol-8 biosynthesis III (2/9 steps found)
- superpathway of menaquinol-8 biosynthesis II (2/10 steps found)
Isozymes
Compare fitness of predicted isozymes for: 2.5.1.90
Use Curated BLAST to search for 2.5.1.90
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (261 amino acids)
>GFF4395 Octaprenyl diphosphate synthase (EC 2.5.1.90) (Variovorax sp. SCN45) MSFTETVMTGVRAAVTGTLTCEAAPVQLAVRLLLSDQQIPIRALVTCSIHSGQQGINAGT ALDLIYISLQQLHAHVDAARGSSALLGNAATVLAGDYLTTGAFRLLVRCDDLQVLALVAD AVNRAAELEATNLKHVQITGDDPAQWLRTRQRLAVPLGEAAGATGATLAGYSDSLAKVAR RYGETLVASCVLLQEADVMDDFVARTTVQRSALDLCRQAMQGARTIATATGNGHPLELAE LIAARINATGHPPGNHMPAPD