Protein Info for GFF4389 in Variovorax sp. SCN45

Annotation: Type IV secretory pathway, VirD2 components (relaxase)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 664 PF11843: DUF3363" amino acids 290 to 661 (372 residues), 486 bits, see alignment E=8.7e-150

Best Hits

KEGG orthology group: None (inferred from 93% identity to tmz:Tmz1t_0320)

Predicted SEED Role

"Type IV secretory pathway, VirD2 components (relaxase)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (664 amino acids)

>GFF4389 Type IV secretory pathway, VirD2 components (relaxase) (Variovorax sp. SCN45)
MSDRRDDDFRVRPSAPKNRGKGQGQSFVSKVLKQTGKASSGKSTVRRPGSAGGTGQRPGS
RLGRGHTAARFAGAKLTPMSRRVTIKTLLVNHQRASPQSLAKHLRYIERDGVGRDGEPGQ
AYGPQTDMADLDAFKERCADDRHHFRFILSPEDGAELEDLRTYTRHLMGRMEADLGTGLD
WVAVNHWNTDNPHTHIVVRGRDDTGKDLIIAGDYIADGFRHRAAELATEWLGPRTELEIR
QTLQREVEQERWTSLDRTLKREMSETGGDGLLHVERLNEPRLQRQRLLLIGRLQRLQRLG
LVEEAKPGIWAVHADAEKTLCTLGERGDIIRTMRRAMRGKPRELAVFEPGDDGRTILGRV
AAKGLADELRDRGYLVIDGADGKAHYVALNARDELANYPTGAVVEVKGSADVRAADKNIA
ELASDGLYRTDHHLAIERGRAKPGRDPQEVVAAHVRRLEALRRAGIVERVAEGLWKVPDD
LAERGRQYDAQRLGGVAVELKSHLPIERQARVIGATWLDQQLIGGGSGLGDLGFGAEAKQ
AMQQRADFLAEQGLAERRGQRVILARNLLGTLRNRELVQAAKDIAAETGLGHRPVADGQR
VAGIYRRSVMLTSGRYAMLDDGMGFALVPWKPVIEQRLGQQLAATVRGGGASWEMGRTRG
PAVS