Protein Info for GFF4384 in Variovorax sp. SCN45

Annotation: Plasmid replication initiator protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 transmembrane" amino acids 180 to 197 (18 residues), see Phobius details PF10134: RPA" amino acids 32 to 261 (230 residues), 296.3 bits, see alignment E=7.9e-93

Best Hits

KEGG orthology group: None (inferred from 99% identity to rso:RSc2606)

Predicted SEED Role

"Plasmid replication initiator protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>GFF4384 Plasmid replication initiator protein (Variovorax sp. SCN45)
VAVAMSSPPGQALPQREQLDLFRALPGDMAPRDSQDLMAFPFFSLAKSRRTAPIDFRSGN
ITIRVEGTAEHGIATIWDADVLIWAASQIVEARDAGIRPSRWIRATPYEILRFIGRSTSL
NDYQRLKAALDRLQSTSIATSIRETTGRRLHRFSWINEWRELADASGTPLGIELILPDWF
YAGVLDAALVLTIDPAYFRLKGGIERWLYRLVRKHGGRQEHGWQFDFKHLHRKSGSAARF
SDFAYDLRALVARQSLPGYVLGIERMPDDGQELLTFRPVLHTARG