Protein Info for GFF438 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: PROBABLE ANTIBIOTIC-RESISTANCE PROTEIN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 PF04909: Amidohydro_2" amino acids 63 to 280 (218 residues), 136.9 bits, see alignment E=5.7e-44

Best Hits

KEGG orthology group: K07045, (no description) (inferred from 67% identity to bch:Bcen2424_0179)

Predicted SEED Role

"PROBABLE ANTIBIOTIC-RESISTANCE PROTEIN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (280 amino acids)

>GFF438 PROBABLE ANTIBIOTIC-RESISTANCE PROTEIN (Hydrogenophaga sp. GW460-11-11-14-LB1)
MRIIDLHCYPGTPTWIESQGPYPAELARYWKRDWVGKTEDDVIAEFTGAGVEACLVALDL
ETTVAAPPCTNEYVHGMWKRHPKRVIQCWGAVEPAKGEIAMIQARKAIRELGFIGFHFHP
IMQHFAVSDRRYYPLFEEINAMGAAVMIDVGTTGMGAGMPGGNGALVRHAHPKHIDQLAA
DFPNLKIIMAHPGWPWVDETTAVALHKGNVYWEMSGWAPKHFPGNLKVDIRGRLQDKIMF
GSDYPSLPYERILREWDELGYKPEVMEKIMHGNAERVLGL