Protein Info for GFF4352 in Sphingobium sp. HT1-2

Annotation: Hydroxylamine reductase (EC 1.7.99.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 546 PF03063: Prismane" amino acids 1 to 539 (539 residues), 518.4 bits, see alignment E=1e-159 TIGR01703: hydroxylamine reductase" amino acids 1 to 543 (543 residues), 700.9 bits, see alignment E=4.8e-215

Best Hits

Swiss-Prot: 57% identical to HCP_BURVG: Hydroxylamine reductase (hcp) from Burkholderia vietnamiensis (strain G4 / LMG 22486)

KEGG orthology group: K00378, hydroxylamine reductase [EC: 1.7.-.-] (inferred from 57% identity to bvi:Bcep1808_5223)

Predicted SEED Role

"Hydroxylamine reductase (EC 1.7.-.-)" in subsystem Nitrosative stress (EC 1.7.-.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (546 amino acids)

>GFF4352 Hydroxylamine reductase (EC 1.7.99.1) (Sphingobium sp. HT1-2)
MYCVQCEQSNKGGCAVKVGSCGKTATVADLQDVLLRVMQGVSAVAARAADKGVRDAEVDA
FTPHAWFTTLTNVNFDEARFLKLIATALRMREKIHAAAMAAGADLSDLPEPATWEPGATL
AELSAAAPMASIQRFVDRDGPSIVGLRDLILYGLKGTAAYSEHARVLGTEEAEVVAEFHR
ISAFLATDPTDVDALLREALAIGALNLKVMELLDAANTGRFGHPEISSVRMTPKAGKALL
VSGHDLGDLEMILQQTEGKGVNVYTHGEMLPANAYPGLKRYPHLAGNYGGAWQDQQKDFA
AFPGAIVMTSNCLINPEIRGYADRLFTAGPVGWAGVRHIVDHDFSPAVARALELPGFAED
APEEVITAGFARNTVMGVADTLLGMIGRGEVKNLFLIGGCDGARPGRNYFHDLAMATPQD
SLILTLGCGKFRFNREELGNIAGVPRVLDMGQCNDAYSAIQVAVAVANALGCGVNDLPLH
YAISWFEQKATAVLLTMLHLGIRKIHLGPTLPQFLTPEVLEVLVEKFDIRPTGEVASDLD
RMLKAA