Protein Info for GFF435 in Sphingobium sp. HT1-2

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 904 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR01782: TonB-dependent receptor" amino acids 46 to 903 (858 residues), 610.2 bits, see alignment E=3.7e-187 PF07715: Plug" amino acids 63 to 169 (107 residues), 66.2 bits, see alignment E=3.6e-22 PF00593: TonB_dep_Rec_b-barrel" amino acids 414 to 871 (458 residues), 125.2 bits, see alignment E=6.7e-40

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (904 amino acids)

>GFF435 TonB-dependent receptor (Sphingobium sp. HT1-2)
VRFSNYRALLSTSAVAAVLLGAMPAAAQDQQQSEQPQQAPEASSEDIVVTGIRSSLQGAL
NAKRNAAQVLDAISAEDIGKFPDKNVGEALQRVTGVQLTRSDGEGSGITIRGADPSLNRV
EINGVTALSTTVGGGRDVDFRDLPSEFVNRLEVVKSATADMTEGGVGGTVRVITRRPFDN
GGKPYLAGSAQAIYADIGDHMDPRLALIGSDTFANGTIGVLVSGTFENRNVESHQARTTG
WVQLKDANGAVYDLNNDGVGDFFPDIPRYVINRLETRRYALNGILEWRPSDDFKAYVESN
WTKSIQSVTSQYLQTGTSGGIVDTENTIIGPDNTVEYLVMTNNTSKAQTSQLGVSYRNIL
GDIKRTTYNVALGADWTTGNLTLTPKISLSKAKAYNNEINATAAVTGMSSLIVDYGNGQN
APNIILPNDPTTTAGINQLTVLRRPRYDDQTEKMAKLDAEYKTDGGLFTSFKIGGQYRDL
TVKSRFYTRTTTLNGFSDPAVQSQIDSIISGNAALGTSPFFHTGNLGFTGDYSGWLNMTQ
GIADAVGIPDPFAEGGCPANADGTCQVYTDTWKVGERNLAGYGQASFAFDVGAVPVSGVI
GARVVNTKVNTSGYLSTGGVISPVSYDSNGTEFLPSINVKAELIPNKLMARATATEVMAR
PLPQQLAPRFTIDVVGLSGSRGNPDLQPFRARQYDAGLEYYINRTSFASVTYFRKEISSF
IQNTTEPYTDASGVTYTITVPTNGTQKVTINGVEAGAQIAFDFIDVPVLKQMGVVANYTY
SKDSGYEGKDYFTGDSLPFQGLSRHAYNISAYYEDDVVSLRGAYNWRSKYLITAQGRGNN
PEFGEAYGQLDASLNVTLMPGISMFLEGVNLLDATRKENANSVERRTIIETVGRRVYGGI
RFKL