Protein Info for GFF4332 in Xanthobacter sp. DMC5

Annotation: Biotin transporter BioY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 37 to 77 (41 residues), see Phobius details amino acids 84 to 108 (25 residues), see Phobius details amino acids 117 to 146 (30 residues), see Phobius details amino acids 155 to 180 (26 residues), see Phobius details PF02632: BioY" amino acids 37 to 179 (143 residues), 114.6 bits, see alignment E=1.8e-37

Best Hits

KEGG orthology group: K03523, putative biotin biosynthesis protein BioY (inferred from 78% identity to xau:Xaut_2005)

Predicted SEED Role

"Substrate-specific component BioY of biotin ECF transporter" in subsystem Biotin biosynthesis or ECF class transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (191 amino acids)

>GFF4332 Biotin transporter BioY (Xanthobacter sp. DMC5)
MENPTFETRTLVRIALIAALIAALGFVPPLYLPLAAGVPITAQSLGVMLAGLLLGSRAGA
AAVGLFVFVVLLGAPLLSGGRGGLGVLASPTAGFLIGYVAGGYVTGLVAERLAARNLPAL
ATALIAAITGGILTVYAFGIPGLAMMAHISLAKAFIGTSVFVPGDLIKAVGAAVLATTVL
RNWSVAAPHRP